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Tential impact of HIV-1 diversity on both vaccine development and the sustainability of antiretroviral therapies, it is particularly important that molecular epidemiological surveillance is continued in HIV diversity hotspots such as Cameroon. In this study we have focused on characterizing the diversity of gag and nef genes of Cameroonian HIV-1 isolates. These genes are?2013 Tongo et al.; license
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D increases permeability of small blood vessels and smooth muscle contraction. In macrophages, eosinophiles, and neutrophils anaphylatoxins can induce oxidative burst, basophiles, and mast cells release histamine, and C3a can enhance the effect of other proinflammatory cytokines such as TNF, IL-6, and SDF-1. While the mechanism for the many reactions precipitated by complement anaphylatoxins has n
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Mpled sequences are likely CRF02_AG (accounting for 50 of HIV-1M infections), with the other "pure" subtypes (G, D, A, and F) and CRFs (CRF11_cpx, 36_cpx, 37_cpx, and CRF01_AE) accounting for the remainder of infections. CRF02_AG and clade G viruses are broadly distributed across west central Africa and have apparently been circulating stably there for many years [3,17-19], consistent with the pr